Disposable quick-release endocavity needle guide is designed for single-use and provides physicians with a tool for performing needle and catheter placement procedures such as deep pelvic and perirectal abscess drainage, core tissue biopsy and larger gauge device placement. Use of the guide allows clinicians to perform one-step catheter placement with ease and accuracy while the instrument path corresponds with on-screen system guidelines. The guide attaches by snapping into the locating features on the transducer, ensuring proper one-step positioning throughout the procedure. The quick-release mechanism allows users to place a catheter or device by removing the "hatch" without the hassle of removing the probe thus eliminating the use of guide wires. The quick-release device is available in convenient procedure kits for varying instrument gauge sizes and lengths.